Biologist - Nuclear Receptors Research

Pharmaceutical Chemistry

Full Time

79939BR

Job Summary

Dr. England's research laboratory (https://pharm.ucsf.edu/england) is developing small molecules to control the activity of nuclear receptors, a class of ligand-regulated transcription factors that play critical roles in human health and disease. The Biologist will characterize the effects of small molecules on the activity of nuclear receptors using cellular assays, including luciferase reporter assays and gene transcription assays (RTqPCR), work up and analyze data (including statistical analyses).

Other aspects of the project may involve developing DNA constructs to explore various aspects of nuclear receptor functioning in cells and characterizing ligand effects on the localization and trafficking of nuclear receptors using appropriate microscopic imaging tools and techniques. Must have prior research laboratory experience, be proficient in aseptic techniques, and be willing/able to design and troubleshoot experiments.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up): TCS Non-Academic Titles Search (ucop.edu)

Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Department of Pharmaceutical Chemistry is one of three departments in the UCSF School of Pharmacy and is under the administrative oversight of the Department Chair, Michelle Arkin.

Through research and teaching, the Department seeks to understand the biological principles of small molecules, proteins, and cellular design, and to apply these principles for the therapeutic benefit of patients

Required Qualifications

• BA/BS in related science including one year of recent/directly related work experience utilizing the techniques/methods required by the position; and/or equivalent experience/training.
• At least one year of experience working with cultured and/or primary cells and carrying out cellular assays in a research laboratory (college laboratory courses are not sufficient).

Preferred Qualifications

• PhD in cellular and molecular biology or related field.
• Knowledge and/or experience with biophysical methods including microscale thermophoresis (MST), Forster resonance energy transfer (FRET), and fluorescence polarization (FP) assays.

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

San Francisco, CA

Campus

Mission Bay (SF)

Work Style

Fully On-Site

Shift

Days

Shift Length

8 Hours

Additional Shift Details

Monday-Friday