Research Associate Scientist - Neurogenesis Research- Lefebvre Lab

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About the Job
This role is an advanced independent researcher that plans, coordinates and executes complex research projects. Works with the Principal Investigator. Participates in and assists in the planning and coordination of research projects, is independent and responsible for a specific aspect of the one or more research projects. Assists in determining the direction of the project. Prepares and writes manuscripts and research proposals, performs data management and quantitative analyses, collaborates in development of innovative research and educational programs, and serves as an educational resource for the laboratory and the Institution.

A research associate scientist position is available in the Lefebvre laboratory at the Children's Hospital of Philadelphia (CHOP) Abramson Research Institute.

The fellow will contribute to a project aimed at elucidating mechanisms whereby SOX5 variants cause Lamb-Shaffer syndrome, a neurodevelopmental disorder characterized by global developmental delay, intellectual disability and autism spectrum disorder features and at testing a gene therapy candidate approach for this disorder in preclinical models. The fellow will use cutting-edge approaches in mouse genetic models, human iPSC-derived brain organoid models, high-throughput 'omics' approaches and gene therapy strategies. Successful accomplishment of this research is anticipated to deepen fundamental scientific knowledge and to increase mechanistic understanding of neurodevelopmental diseases and our ability to treat them. It is also anticipated to help the fellow launch a promising career as an independent research investigator.

What you will do

• Assists faculty in the conduct of research of significant value in the basic and/or translational science area
• Functions with a high level of independence in the development and execution of research projects
• Plans, conducts, and manages research projects within the federal, institutional regulations and policies
• Collaborates with researchers, external agencies and institutions to develop cooperative research initiatives
• Trains technical staff, students, fellows, and physicians in lab procedures
• Reviews manuscripts for peer-reviewed journals
• Assist in composing/developing applications for grants, contracts, and research funding proposals.
• Responsible for appropriate use of research funds
• May supervise students or other research staff as assigned.

Education

• Bachelor's Degree Required
• Master's Degree Preferred
• Doctorate Preferred

Experience

• At least eight (8) years of directly relevant post grad scientific lab experience Required
• At least ten (10) years of directly relevant post grad scientific lab experience Preferred
• Successful completion of a Post Doc Fellowship Preferred

Knowledge, Skills and Abilities

• Expert knowledge in the use of a wide variety of lab techniques, research equipment and research related software
• Excellent verbal and written communications skills
• Excellent organizational skills
• Excellent critical thinking / problem-solving skills
• Excellent analytical skills
• Strong interpersonal skills
• Solid leadership skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

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SALARY RANGE:

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.