New 
Postdoctoral Associate - Methods Development Lab
 Broad Institute | |
paid time off, paid holidays, 401(k), retirement plan
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 United States, Massachusetts, Cambridge | |
 May 19, 2026 | |
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Description & Requirements The Broad Institute of MIT & Harvard is seeking an outstanding and innovative Computational Scientist to join the Methods Development Lab. The core mission of this role is the development of novel, scalable computational methods and robust analytical pipelines for the interrogation of ultra high-throughput single-cell multiomic data. This includes, but is not limited to, advanced analyses of transcriptomics, proteomics, epigenomics, and large-scale perturbation (e.g., Perturb-seq) datasets.The combination of molecular and computational advances over the past decade has substantially augmented our ability to create transformative methods. While this accelerated pace of method development offers great promise, the rapid expansion of novel techniques gives rise to new challenges in effective adoption and implementation. To capitalize on these exciting advances, the Broad Institute has formed the Methods Development Lab (MDL), with the mission of identifying key scientific frontiers, generating high-performance end-to-end methods, and driving cutting-edge applications with collaborators across the research community.
Postdoctoral Researcher:
We are seeking a Postdoctoral Researcher to drive the development and evaluation of advanced perturbation technologies. A core mission of the MDL is to engineer highly scalable and robust tools that push the boundaries of functional genomics. In addition to scale, we have a strong research emphasis on creating advanced library construction techniques that increase capture efficiency and enable multimodal measurements. The Postdoctoral Researcher will drive key projects in this space, executing on project plans, communicating progress, and fostering strong and productive collaborations. In addition to methods development, The Postdoctoral Researcher will drive application of these novel methods at the Broad Institute and work closely with production teams to translate novel methods into production scale processes to make them available to the community. *** PLEASE INCLUDE A COVER LETTER WITH YOUR APPLICATION ***
RESPONSIBILITIES
* Design and drive technology development projects. * Work closely with computational biologists to create analytic methods for novel technologies and resources for the community. * Work closely with productionization teams. * Set and communicate goals, priorities, timelines, and budgets for projects. * Track and report progress in a clear and organized fashion. * Assists and actively participates in obtaining federal, philanthropic, institutional, or industrial funding opportunities. * Publish novel methods. * Present work both internally and externally. * Seek intellectual property protection for inventions that are conceived of or developed while a member of the MDL. * Provide strategic guidance to the MDL Group Leader SKILLS AND ABILITIES
* Strong individual contributor with the ability to quickly pivot and collaborate with key stakeholders and senior leadership * Must be forward-thinking and innovative, with a nimble scientific/technical mind, able to rapidly
develop and execute on creative solutions. * Extensive molecular biology experience. * Extensive experience with single-cell technologies. * Extensive experience developing methods. * Must be skilled at supervising or interacting with teams of researchers, providing both scientific mentorship and direction. * Must be proficient in setting goals, priorities, and budgets to drive efficient project execution. * Strong data analysis skills. QUALIFICATIONS
* PhD in Molecular Biology The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.
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