Senior Research Technologist

Department: MED-Pathology
Salary/Grade: NEX/15

Target hiring range for this position will be between be range is as be $27.06-$33.83 per hour. Offered salary will be determined by the applicant's education, experience, knowledge, skills and abilities, as well as internal equity and alignment with market data.

Job Summary:

The main research scope of Zhang lab is to understand how genetic and epigenetic factors orchestrate to facilitate blood malignancies. The candidate is expected to apply a diverse range of molecular, immunological, histological, and cellular skills and use animal models (mouse and xenograft).

Please note: sometimes extended hours around experiments and animal work will be required

Specific Responsibilities:

• Acting as a technical expert or specialist in a particular field within a research lab, establishes and optimizes protocols and coordinates conduct of multiple complex experiments.
• Reviews results and revises protocols as necessary to ensure that project objectives are attained.
• Using an expert level of skill, completes the following activities

Molecular Biology:

• DNA, RNA, Protein isolation, purification and expression
• Southern, Northern, Western blotting
• PCR, RT-PCR
• Plasmid preparation
• Cloning, mapping and sequencing of DNA
• Recombinant virus production and purification

Cellular Biology:

• Cell culture, cell isolation
• Functional studies
• Transfection

Histology:

• Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
• Immunohistochemistry
• Microscopy

Immunology:

• Flow cytometry
• ELISA, Elispot assay
• Cytokine assay
• Antibody production and purification

Animal:

• Husbandry
• Breeding and screening transgenic mice
• Dissections
• Blood collection
• Surgical procedures
• Database management of colony

Administration

• Oversees and manages lab databases which may include ensuring that experiments are observed and that data is collected and entered correctly.
• Reviews and analyzes data.
• Creates computer models, graphs, reports and summaries for use in publications, professional journals, and grant applications.
• Co-authors scientific papers for presentation and publication.
• Researches and obtains funding.
• Creates and maintains lab manuals regarding operating, safety, and etc. procedures.

Finance

• Creates lab financial plan and budget/audit expenses.
• Obtains sales quotes for lab equipment and supplies.
• Reviews and adjusts expenses to decrease costs.
• Oversees repair and maintenance of all lab equipment.
• Ensures that lab supplies are ready and available when necessary.

Supervision

• Trains, directs, assigns duties to and may supervise lab EEs, students, residents and/or fellows.

Miscellaneous

Performs other duties as assigned.

Preferred Competencies: (Skills, knowledge, and abilities)

• Basic laboratory skills including solid basic math and chemistry knowledge are required. The candidate is expected to be capable of using pipettors (including serological pipettors), following protocols to make buffers, assemble PCR or other molecular reactions; capable of scale-up/down the existing protocol according to reaction numbers; capable of handling mice or capable of learning mouse handling and other related techniques. It is also expected that the candidate has a positive attitude at work and is with excellent work ethics. The candidate is also anticipated to be capable of working with flexibilities in hours and deadlines. Excellent bookkeeping skills (specially, attention to deal and organization skills) and communication skills are essential for this position.

Benefits:
At Northwestern, we are proud to provide meaningful, competitive, high-quality health care plans, retirement benefits, tuition discounts and more! Visit us at https://www.northwestern.edu/hr/benefits/index.html to learn more.

Work-Life and Wellness:
Northwestern offers comprehensive programs and services to help you and your family navigate life's challenges and opportunities, and adopt and maintain healthy lifestyles.
We support flexible work arrangements where possible and programs to help you locate and pay for quality, affordable childcare and senior/adult care. Visit us at https://www.northwestern.edu/hr/benefits/work-life/index.html to learn more.

Professional Growth & Development:
Northwestern supports employee career development in all circumstances whether your workspace is on campus or at home. If you're interested in developing your professional potential or continuing your formal education, we offer a variety of tools and resources. Visit us at https://www.northwestern.edu/hr/learning/index.html to learn more.

Northwestern University is an Equal Opportunity Employer and does not discriminate on the basis of protected characteristics, including disability and veteran status. View Northwestern's non-discrimination statement. Job applicants who wish to request an accommodation in the application or hiring process should contact the Office of Civil Rights and Title IX Compliance. View additional information on the accommodations process.