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Global Value & Access Strategy Director - CF

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Feb 11, 2026

Job Description

General Summary: The Director, GVAS CF Pipeline role will join GVAS and serve as Market Access Lead within our CF portfolio focused on the development of pipeline assets. The individual will be responsible for leading the development of Global Market Access strategies for the CF pipeline, ensuring that enterprise planning will enable optimal patient access. This position reports to the Head of CF & Rare Disease Global Market Access within GVAS. Key Responsibilities:
  • Lead payer strategic planning to support value and access optimization for the CF pipeline
  • Lead development and refinement of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process
  • Accountable for Global Payer Plans, which integrate value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing
  • Ensure the payer position is consistently represented to internal stakeholders and ensure robust strategic input into commercialization and development decisions
  • Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs
  • Inform financial forecasts
  • Partner with HEOR and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement
  • Lead capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment
  • Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly
  • Collaborate closely with HEOR, International P&R, Corporate Affairs, US Managed Markets, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization
Qualifications:
  • 7+ years of direct biotechnology / pharmaceutical industry experience and/or payer experience
  • Deep working knowledge of both US and ex-US healthcare and HTA systems required
  • Rare disease experience strongly preferred
  • Experience in comparable Global role in a matrix organization preferred
  • Experience in Market Access and Pricing throughout the product lifecycle (from early development through LoE) preferred
  • Demonstrated ability to think strategically and make sound pricing and market access recommendations
  • Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex
  • General experience in commercialization and drug development
  • Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex
  • Strong executive communication skills and experience
  • Demonstrated relationship building at all levels of the organization and across geographies
  • Recognized as a team player with excellent interpersonal skills who is flexible and reliable
  • Displays sound ethics and a fit for Vertex's core values
Education: BA/BS in field of study requiring quantitative analysis; Advanced degree preferred

Pay Range:

$212,000 - $318,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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