Are you passionate about making the world better? Are you looking for an organization that aligns with your values?
MRIGlobal solves challenging problems through science, engineering, and program management. We are an independent scientific research organization dedicated to benefiting society and fostering a safe, healthy, and sustainable environment.
When you embark on a career with MRIGlobal, you are joining a crew of world-class talent and problem solvers. Established in 1944, MRIGlobal is headquartered in Kansas City, MO, working in several states including Virginia and Maryland.
Location: Kansas City, MO (Remote)
Organization: MRIGlobal - Integrated Pharmaceutical Solutions
Basic Function / Nature & Scope
The Program Manager II leads cross-functional programs in early-phase pharmaceutical development and clinical supply chain operations, ensuring technical excellence and phase-appropriate cGMP compliance. This is an ideal role for a seasoned professional who enjoys the rigor of science but prefers the broader scope of program management. This role oversees Chemistry, Manufacturing, and Controls (CMC) activities for investigational drug products, including drug substance and product development, analytical testing, stability studies, and packaging/distribution for Phase I/II clinical trials. The Program Manager II serves as the primary liaison between clients, internal teams, and external vendors, driving program success from initiation through closeout.
Essential Functions
- CMC Technical Leadership: Oversee drug substance and product development, analytical method development and validation, release and stability programs for IND-enabling and early-phase clinical studies.
- Clinical Supply Chain Oversight: Oversee manufacturing, packaging, labeling, storage, and distribution of clinical trial materials, ensuring supply continuity.
- Regulatory Support: Ensure compliance with cGMP and ICH guidelines. Oversee technical investigations, change controls, and deviations for all program-related activities.
- Risk Management: Identify and mitigate risks across the drug development spectrum-from formulation challenges in novel compounds to procurement constraints for commercial products (e.g., securing single-lot bulk supply and managing expiration dating of commercial stock)-before they impact clinical timelines.
- Vendor & CDMO Management: Coordinate with external partners for manufacturing and testing activities, holding them accountable.
- Program Management: Develop budgets, monitor and control costs, negotiate scope changes, track milestones, and ensure the timely submission of high-quality deliverables. Lead internal technical meetings and client-hosted updates.
Minimum Qualifications
- Advanced degree (Ph.D. or M.S.) in Pharmaceutical Sciences, Chemistry, or a related scientific discipline
- Minimum of 7 years (Ph.D.) or 10 years (M.S.) of relevant experience
- Strong knowledge of FDA cGMP regulations and FDA and ICH guidelines.
- Proven experience managing complex projects and overseeing external vendors.
- Excellent leadership, organizational, and communication skills.
- Ability to travel as required (approx. 5%).
Preferred Qualifications
- Project Management Professional (PMP) Certification
- Prior work experience with a contract research organization (CRO) or contract development manufacturing organization (CDMO)
- Experience working on U.S. government-funded contracts (e.g., NIAID, NCI, NCATS).
- Strong publication record or history of technical presentations in the field of drug development.
Pay Range $128,000 - $141,000
The salary range is intended as a general guideline and is not a guaranteed offer, as compensation depends on various factors such as scope and responsibilities of the position, candidate qualifications, experience, internal equity, and market conditions. MRIGlobal also provides a comprehensive benefits package, including health and life insurance, disability coverage, gym reimbursement, mental health support, paid holidays, and PTO.
WHAT WE OFFER
At MRIGlobal, we offer benefits and perks that make your life even better.
Your Well-Being: You can receive comprehensive coverage for you and your family, and resources that support mental, physical, social, and financial well-being. Get access to wellness benefits like virtual coaching, no-cost counseling, onsite health screenings, gym reimbursement, and more. MRIGlobal has received multiple wellness recognitions, including being named "Healthiest Employer" by Kansas City's Business Journal in 2024.
A Bright Future: MRIGlobal offers award-winning employer retirement matches and no-cost financial education benefits. Get paid Parental Leave. Enjoy PTO, and a flexible culture that encourages work-life integration.
Personal Development: At MRIGlobal, you will enjoy diverse work that will grow your skillset, along with a tuition reimbursement option to pay for higher education.
A Genuine Community: MRIGlobal is a special workplace. From our Chili Cook-offs, Pi Day, and charitable giving opportunities, our traditions strengthen our team spirit. Join our seasonal staff events, DEI celebrations, and volunteer in initiatives that nurture future STEM generations.
To view all of MRIGlobal's current openings and to ensure that we receive your resume, visit our Career page.
EOE, including disability/vets. As an organization dedicated to scientific advancement, MRIGlobal invites and embraces diversity in our people. We value their unique backgrounds and perspectives in every aspect of our mission. We are committed to creating a safe, welcoming, and inclusive environment where everyone feels respected and represented, fostering a culture where all input is welcome. We adapt to change, challenge the status quo, and evolve through belonging, allyship, and mutual support.
Certain roles, depending on the nature of the job or work assignment require adherence to specific safety measures, including up-to-date vaccinations. This requirement aligns with both our operational needs and the expectations of our clients. Employees must furnish proof of such vaccinations before commencing their duties. Should an individual be unable to meet this vaccination criterion due to a legitimate medical condition, disability, pregnancy, or religious belief, we offer the option to apply for a reasonable accommodation in line with applicable laws. Inquiries or requests for accommodations should be directed to accessibility@mriglobal.org, ensuring a prompt and considerate resolution process. It's important to note that failure to comply with a vaccination-required role or to secure an approved accommodation may affect one's employment status with our organization.
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MRIGLOBAL
life insurance, parental leave, paid holidays, tuition reimbursement
Jan 15, 2026