Senior Manager, Health Economics and Outcomes Research (HEOR)

Sirtex Medical is a global leader in healthcare, with offices in the U.S., Australia, Germany, and Singapore, dedicated to improving patient outcomes.

Our mission is to be at the forefront of minimally invasive cancer and embolization therapies. By partnering with physicians, we aim to provide innovative products that enhance patient outcomes and simplify treatments. Achieving this ambitious goal requires passionate and talented individuals who are committed to making a difference. Our flagship product, SIR-Spheres Y-90 resin microspheres, is a targeted radiation therapy for liver cancer. To date, we have delivered over >150K doses across 50+ countries, significantly impacting patients' lives worldwide. Our success is fueled by our dedication to serving the medical community, maintaining professionalism, fostering a collaborative work culture, nurturing an entrepreneurial spirit, and continuously pursuing innovation and improvement.

At Sirtex, we are committed to creating a great workplace. We offer a range of benefits, programs, and services to support our employees, ensuring they have opportunities to contribute to our success and advance their careers. Join our inclusive community, where you can collaborate with talented colleagues, bring your ideas to life, and advance your career, all while delivering innovative healthcare solutions to patients.

The Senior Manager, HEOR will play a leading role in developing and executing U.S.-focused health economics and outcomes research strategies, while also providing strategic support for global HEOR activities across key regions such as the EU and Japan. This role will focus on current portfolio and early/ late-stage assets to support market access, pricing, and reimbursement through the generation of high-quality economic evidence and real-world data.

The ideal candidate will have strong expertise in the U.S. payer landscape and evidence expectations (CMS, ICER, commercial payers), combined with experience or familiarity with international HTA processes and reimbursement frameworks (e.g., NICE, G-BA, MHLW).

NOTE:Candidates must be available to work onsite with a hybrid schedule (Currently minimum of 3 days in office and 2 days remote).

Key Responsibilities:

U.S. Strategy and Execution (Primary Focus):

• Lead U.S. HEOR strategy to support access, reimbursement, and pricing decisions across the product lifecycle.
• Evaluate early-stage pipeline assets to inform U.S. commercial potential, pricing thresholds, and evidence requirements.
• Design and oversee U.S.-specific economic models (e.g., cost-effectiveness, budget impact) and real-world evidence (RWE) studies (claims, EMR, registries).
• Develop and maintain U.S. AMCP dossiers, ICER submission materials, and payer value communication tools.
• Provide insights on U.S. reimbursement pathways (e.g., Medicare Part B vs. D, buy-and-bill, coding, coverage) and support value-based contracting strategies.

Global Support (EU, Japan, and Other Priority Markets):

• Collaborate with global HEOR and affiliate teams to align on evidence generation strategies that meet international HTA requirements (e.g., NICE, HAS, IQWiG, MHLW).
• Provide input into global health economic models, global value dossiers (GVDs), and clinical trial design to ensure payer-relevant endpoints and data are captured.
• Contribute to the development of region-specific adaptations of economic models and RWE studies based on local data and assumptions.
• Support pricing and reimbursement submissions in international markets by aligning U.S. insights with global strategies.

Cross-Functional Collaboration:

• Partner closely with U.S. Market Access/ Reimbursement, Medical Affairs, Clinical Development, Business Development, Regulatory, and Commercial to shape integrated access strategies.
• Coordinate with global and regional HEOR counterparts to ensure consistency of value messaging and evidence planning.
• Manage external vendors, academic collaborators, and consultants to ensure timely and high-quality execution of projects.

Communication and Dissemination:

• Present HEOR data at internal forums, scientific congresses (e.g., ISPOR, AMCP), and contribute to peer-reviewed publications.
• Translate technical findings into impactful insights and recommendations for internal stakeholders and external decision-makers.

Education:

• Advanced degree (PhD, PharmD, MPH, MS, or equivalent) in Health Economics, Public Health, Epidemiology, Pharmacy, or a related field.

Experience:

• Minimum 5-8 years of HEOR experience in the pharmaceutical, biotechnology, or healthcare consulting industry.
• Strong background in U.S. payer evidence requirements, pricing and reimbursement processes, and health policy landscape.
• Familiarity with international HTA systems and value assessment methodologies (e.g., NICE, ICER, IQWiG, MHLW).
• Hands-on experience developing economic models and managing RWE studies.
• Experience supporting both pre-launch and post-launch assets.
• Therapeutic area experience in oncology, rare disease, or specialty therapeutics.

Skills:

• Strategic mindset with the ability to balance U.S. and global evidence needs.
• Excellent project management skills and vendor oversight.
• Strong scientific writing and communication skills, including the ability to translate complex analyses into clear insights.
• Collaborative and team-oriented, with experience working in a global matrix environment.
• Entrepreneurial, resourceful, tenacious and diplomatic.
• Flexible and adaptable style with the ability to learn and assimilate information quickly.
• Committed to deliver high quality results on time
• Resilient and able to remain solution focused in challenging situations

The target base salary range for this position will range from $156,000,000 to $196,000 annually.Individual compensation for this job requisition will be based on non-discriminatory factors, including your geographic location, skills, experience, education and other factors as they relate to the position requirements. Actual compensation may vary depending on the confirmed job-related skills and experience.

In addition to the expected base compensation, this role is eligible to participate in Sirtex's incentive programs (target bonus of 15%for this position)and benefit plans, which include paid sick and vacation time, health insurance and a generous 401k matching program.

All your information will be kept confidential according to EEO guidelines.

Do you want to be part of something bigger? A team whose impact stretches across the globe making a real difference to the quality of people's lives. Sirtex recognizes that well-being, financial health, and work-life balance are crucial for our employees to achieve personal success.

Sirtex offers qualified candidates:

• Diverse and flexible work arrangements to achieve the optimum balance between work and personal responsibilities.
• A culture of respect, diversity, collaboration, and innovation fostering inclusiveness and superior performance.
• Attractive compensation and benefit packages which are practical, robust and equitable.
• A commitment to support ongoing professional growth through career development, on the job experiences and training opportunities.
• Challenging work which supports the development of new and better ways to improve clinical outcomes for oncology treatment around the world.
• An unwavering commitment to company values, employee safety and excellence in everything we do.

Diversity drives innovation; inclusion fosters belonging, growth and success. Sirtex believes that it takes multiple perspectives and voices to create a culture and workplace which fosters engagement, teamwork, and employee satisfaction to perform our best and deliver on commitments. We are dedicated to fostering an environment where all employees feel valued, included, and can share their ideas so that we can exceed even our own expectations.

Sirtex is An Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age or any other characteristic protected under applicable law. Sirtex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.