Scientist, Engineering

Description

The purpose of this role is to provide engineering support to Phlow's Manufacturing Science and Technology (MS&T) group. This is an exciting opportunity for recent graduates or individuals with process engineering experience to independently design, install, and operate continuous and batch processing equipment under the direction of a Principal Scientist or other team member. The candidate will provide engineering support to the MS&T group including equipment selection and design, heat and mass transfer calculations, and scale-up modelling. The candidate will support execution Phlow's internal API development projects as well as the CDMO business to ensure business objectives are met. The candidate will ensure excellence of our process development and technical transfer to Phlow's partners or customers. The candidate will personify Phlow's shared values and culture, both internally and externally. The candidate will work with the highest standards of safety, integrity, transparency, and ethics to create win-win scenarios for patients, customers, partners, and colleagues.

Responsibilities:?

• Provide engineering support to Phlow's MS&T labs to ensure the deliverables to customer's projects are met on time and on budget.
• Independently design, install, and operate continuous and batch processing equipment
• Perform relevant calculations and modelling for scale-up of batch and continuous processes
• Maintain accurate, legible, and complete records of all experiments and observations.
• Author progress reports and present scientific results to team members.
• Exhibit a high level of safety awareness and conduct lab operations in a safe manner.
• Participate in the ongoing continuous improvements in manufacturing processes resulting in improving product quality, robustness, and cost.
• Collaborate with Analytical Chemistry, EH&S, Engineering, Project Management, Quality Assurance and Regulatory Affairs to ensure strong working relationships with all partners and Phlow employees.

Requirements

• 0 - 5 years working in related roles in the pharmaceutical industry
• Experience installing, operating, and maintaining processing equipment for batch and continuous pharmaceutical processes
• Experience with heat and mass transfer calculations in batch and continuous processes
• Experience with process modelling and computational software (ex., Dynochem, ReactionLab, gPROMS, etc)
• Strong interpersonal and communication skills

Preferred Qualifications:

• BS or MS in Chemical engineering
• Process chemistry and API manufacturing experience is a plus.
• Experience with generic API development, technology transfer, and manufacture is a plus.
• Knowledge of ICH and cGMP requirements is a plus.
• Experience with design of experiments (DOE) and related multivariate experimentation approaches is a plus.
• Experience with the development and implementation of continuous flow manufacturing processes is a plus.