Senior Manager, Clinical Supply Chain

Ardelyx
life insurance, parental leave, paid holidays, flex time, 401(k)
United States, Massachusetts, Waltham
Jun 18, 2025
Description Ardelyx is a publicly traded commercial biopharmaceutical company founded with a mission to discover, develop and commercialize innovative first-in-class medicines that meet significant unmet medical needs. Ardelyx has two commercial products approved in the United States, IBSRELA (tenapanor) and XPHOZAH (tenapanor). Ardelyx has agreements for the development and commercialization of tenapanor outside of the U.S. Kyowa Kirin commercializes PHOZEVEL (tenapanor) for hyperphosphatemia in Japan. A New Drug Application for tenapanor for hyperphosphatemia has been approved in China with Fosun Pharma. Knight Therapeutics commercializes IBSRELA in Canada. Position Summary: We are searching for a highly motivated Senior Manager, Clinical Supply Chain. Reporting to the Vice President, Supply Chain, the desired candidate will be responsible for managing investigational drug supplies for clinical trials. The candidate will be responsible for all aspects of clinical supply management including forecasting, labeling distribution, monitoring inventory and IRT vendor oversight. This is a fantastic opportunity to join a small team and have a significant impact in addressing unmet patient needs by advancing Ardelyx's novel pipeline. Responsibilities: Responsible for all aspects of clinical supply management including forecasting, packaging, labeling, distribution, inventory monitoring and IRT vendor oversight Serve as the primary point of contact and collaborate with clinical operations to forecast demand Partner closely with CMC team to develop comprehensive supply plans taking into account anticipated demand and shelf-life limitations Manage external CDMO for clinical packaging and labeling operations Administer, review and approve pre and post-production documentation of clinical supplies Provide logistical management for global shipments of clinical trial material shipments. Manage Interactive Response Technology (IRT) systems from initial design to implementation and management Manage clinical label design and approval Establish clinical supply processes and author associated SOPs Mitigate supply chain operational risks and drive continuous improvement within the clinical supply chain function Qualifications: Bachelor's degree in business administration, supply chain management or related discipline, with 6 - 9 years of clinical supply chain experience in pharmaceutical industry or equivalent experience Experience virtually managing CMO/CROs Experience with CTM planning Experience in managing IRT vendors Solid understanding of cGMPs, clinical operations, and development processes Strong communication and leadership skills, including ability to communicate effectively with people individually and groups Strong analytical skills with the proven ability to effectively analyze data to determine trends and inform strategy. Proficient with Microsoft Office Suite or related software Strong analytical skills with the ability to identify and resolve complex supply chain issues Detailed oriented with ability to manage multiple projects in a fast-changing environment The anticipated annualized base pay range for this full-time position is $152,000-$186,000. Ardelyx utilizes industry data to ensure that our compensation is competitive and aligned with our industry peers. Actual base pay will be determined based on a variety of factors, including years of relevant experience, training, qualifications, and internal equity. The compensation package may also include an annual bonus target and equity awards, subject to eligibility and other requirements. Ardelyx also offers a robust benefits package to employees, including a 401(k) plan with generous employer match, 12 weeks of paid parental leave, up to 12 weeks of living organ and bone marrow leave, equity incentive plans, health plans (medical, prescription drug, dental, and vision),life insurance and disability, flexible time off, annual Winter Holiday shut down, and at least 11 paid holidays. Ardelyx is an equal opportunity employer.