Scientist - CryoEM - Protein Technology Center

St. Jude Children's Research Hospital
$86,320 - $154,960
United States, Tennessee, Memphis
262 Danny Thomas Place (Show on map)
Apr 11, 2025
Protein Technologies Center (PTC) within the Department of Structural Biology is seeking a scientist with experience in CryoEM and protein purification to understand the function and biology of the disease by determining the three-dimensional structures of proteins at atomic resolution. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. The PTC is a multidisciplinary team with capabilities in protein engineering, cloning, expression, purification, biophysical analysis of proteins, and structure determination. Cryo-electron microscopy has enabled us to image and obtain structures at high resolutions. This Scientist position is a bench-based role where the Scientist will purify protein, vitrify samples, collect data, process, analyze, and build models. The Scientist will manage projects, collaborate, and contribute to a deeper understanding of biology by analyzing the structures. Responsibilities: Cloning, expressing and purifying the proteins and their complexes. Vitrification of biological macromolecules Processing CryoEM images, image analysis, and building models Interpret the structures and write manuscripts based on findings Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. PhD in the area of molecular biology, biochemistry, protein engineering, or any related discipline preferred. Minimum Experience: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Preferred Experience: PhD (with at least 3 years of postdoctoral experience) in structural biology or any related discipline. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can "Have More in Memphis." Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist - CryoEM - Protein Technology Center. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.